贝类遗传与演化研究室
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韩文韬

博士，副教授，硕士生导师

中国海洋大学“青年英才”第二层次

研究方向：海洋生物基因组学与宏观演化研究

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教育经历

2012-2016，大连海洋大学，海洋科学，学士

2016-2019，上海海洋大学，海洋科学，硕士

2019-2023，中国海洋大学，海洋生物学，博士

工作经历

2023-2025，中国海洋大学，生物学，博士后

2025至今，中国海洋大学，副教授，硕士生导师

主要研究方向及成果

主要围绕海洋生物基因组数据挖掘、重要性状遗传调控及环境适应机制解析等方向开展系统研究，以第一/通讯作者（含共同）在 Science、Nature Ecology & Evolution（2篇）等国际期刊发表 SCI 论文10余篇。代表性成果包括：●构建跨动物界心脏分子演化全景图谱，揭示动物“原始心脏”起源及其“核心基因工具包逐步叠加”的演化模式（Science）；●攻克同形性染色体难以组装、鉴定和比较的难题，发现双向性别偏好基因在性别分化和性腺发育中的关键作用，揭示同形性染色体维持机制（Nat. Ecol. Evol., 封面文章）；●突破海洋生物遗传解析技术瓶颈，解析海洋生物适应高盐、低温、UV等多重环境压力的遗传基础（Nat. Ecol. Evol., 专题评述）。

主持项目

  1. 国家自然科学基金青年基金项目（C类），2025-2027
  2. 中国科协青年人才托举工程，2023-2025
  3. 国家博士后资助计划，2023-2025
  4. 山东省博士后创新人才计划，2023-2025
  5. 中国海洋大学“青年英才工程”第二层次科研启动经费，2026-2028

代表性成果（#共同第一；*通讯作者）

  1.  Lian, S.#, Wang, W.#,*, Liu, Y.#, Lu, M.#, Han, W.#, Luo, J.#, Zhang, X.#, Pang, Y.#, Li, Y.#, Li, Y., Dang, X., Wang, P., Qin, Y., Tan, N., Zhang, F., Zhang, J., Gao, S., Zhang, R., Guo, L., Jiang, L., Zhang, P., Zhang, Y., Qu, Z., Pan, S., Zhang, Y., Hu, N., Chen, Y., Cao, Y., Li, W., Chen, X., Shi, J., Yang, S., Li, Y., Song, Q., Bao, L., Li, Y., Liu, X., Wang, J., Zhang, L., Li, R., Yu, X., Yang, T., Chen, J., Li, L., Zhang, M., Li, L., Zhang, R., Li, H., Gu, Y., Xu, X., Yang, H., Bao, Z., Burns, CG., Burns, CE., Kelly, RG., Wang, J., Zhao, Y., Su, Y., Fan, G., Liu, Q.*, Wang, S.*, Fei, J.*, Pan, S.*, Zhao, L.*. (2026) Spatially resolved single-cell atlas reveals the macroevolutionary trajectory of animal hearts. Science. (Online advanced publication, https://www.science.org/doi/10.1126/science.adw0855)
  2.  Han, W. #, Liu, L. #, Wang, J. #, Wei H. #, Li, Y. #, Zhang, Lj. #, Guo, Z., Li, Y., Liu, T, Zeng, Q., Xing, Q., Shu, Y., Wang, T., Yang, Y., Zhang, M., Li, R., Yu, J., Pu, Z., Lv, J., Lian, S., Hu, J., Hu, X., Bao, Z., Bao, L.*, Zhang, Ll.*, Wang, S.*. (2022). Ancient homomorphy of molluscan sex chromosomes sustained by reversible sex-biased genes and sex determiner translocation. Nature Ecology & Evolution 6, 1891-1906. (Cover story,  Behind the Paper: The 'forever-young' secret of scallop sex chromosomes: exceptions to the 'general' rules)
  3. Ye, N. #,*, Han, W. #, Toseland, A, Wang, Y., Fan, X., Xu, D., Oosterhout,C, Sea of Change Consortium, Grigoriev, I., Tagliabue, A, Zhang, J., Zhang, Y., Ma, J, Qiu, H., Li Y., Zhang X *, Mock, T.*. (2022). The role of zinc in the adaptive evolution of polar phytoplankton. Nature Ecology & Evolution 6, 965-978. (NEE News & Views: Polar algae flaunt their zinc assets)
  4. Han W., Wu S., Ding H., Wang M., Wang M., Bao Z., Wang B.*, Hu J.*.(2023). Improved chromosomal-level genome assembly and re-annotation of leopard coral grouper. Scientific Data 10, 156.
  5. Li, S.#, Wang, D.#, Liu, T., Liu, S., Ni, K., Zhang, L., Wang, S., Han, W.*, Bao, L.*. (2026) Development of structural variation-based sex-specific markers and a non-destructive visual assay for sex identification in the sea cucumber (Apostichopus japonicus). Aquaculture 625: 744339.
  6. Wu, S.#, Zeng, Q.#, Han, W.#, Wang, M., Ding, H., Teng, M., Wang, M, Li, P, Gao, X., Bao, Z., Wang, B.*, Hu, J.*. (2023). Deciphering the population structure and genetic basis of growth traits from whole-genome resequencing of the leopard coral grouper (Plectropomus leopardus). Zoological Research. 45(2) 1-12.
  7. Chen, C., Lium J., Zhuangm R., Nim K., Wangm M., Lim Y., Wangm J., Wang, S., Han, W.*, Bao, L.*. (2026) Genome-wide 6mA map unveils epigenetic adaptation in deep-sea limpet. Ecology and Evolution. 16: e73449.
  8. Zhang, X.#, Han, W.#, Fan, X., Wang, Y., Xu, D., Sun, K., Zhang, Y., Ma, J., Ye, N.*. (2023) Gene duplication and functional divergence of new genes contributed to the polar acclimation of Antarctic green algae. Marine Life Science Technology 5(4), 511–524.
  9. Yu, X.#, Zhao, B.#, Han, W.#, Liu, Y.#, Wang Z, Zhu X, Wang Y, Fang L, Wang S, Hu J, Bao Z. (2026) The first near-complete telomere-to-telomere genome of Atlantic salmon (Salmo salar) provides insights for genetic diversity. The Innovation Life. 4: 100236.
  10. Teng, L. #, Han, W.#, Fan, X., Zhang, X., Xu, D., Wang, Y., Rahman, S., Pellegrini, M., L. Mock, T., Ye, N.*. (2021). Integrative analysis of chloroplast DNA methylation in a marine alga—Saccharina japonica. Plant Molecular Biology 105, 611–623. (Cover story)
  11. Han, W., Fan, X., Teng, L., Kaczurowski, M.J.S., Zhang, X., Xu, D., Yin, Y., and Ye, N.*. (2019). Identification, classification, and evolution of putative xylosyltransferases from algae. Protoplasma 256, 1119-1132.
  12. Chen, X.#, Han, W.#, Chang, X., Tang, C., Chen, K., Bao, L., Zhang, L., Hu, J., Wang, S.*, Bao, Z.* (2025) .   High-quality genome assembly of the azooxanthellate coral Tubastraea coccinea (Lesson, 1829) . Scientific Data 12, 507.
  13. Chang, X .#, Han, W.#, Chen, X., Tang, C., Wang, D., Huang, H., Li, Y., Chen, K., Hu, J., Bao, Z., Chen, H.*, Wang, S.*(2025) .  Re-annotation improved large-scale assembly of the reef-building coral Acropora intermedia. Scientific Data 12, 1504.
  14. Tang, C., Han, W.*, Ke, S., Wang, D., Chen, K., Bao, L., Guan, L., Hu, J., Wang, S., Bao, Z. (2025). Complete mitochondrial genome and phylogenetic analysis of Podabacia crustacea (Pallas, 1766). Mitochondrial DNA Part B, 10(7), 537–542.
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